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Browse Lab Results > 2014-0245

Trial Summary

About CDAS Project, PI, Publications: Validation of findings from the Epigenome-Wide Association Study of Breast Cancer

Datasets


Site: Breast

Inclusion Criteria:

  • Intervention Arm Females
  • No Rare Cancers
  • No Prior History of Any Cancer
  • T0 DNA Extracted from 2009-00553 or T0 Source Available
  • Pre-Exit T0 DNA Extracted from 2009-00553 or T0 Source Available
  • T0 Material is 4-7 Years Pre-Dx (Cases)
  • Source Material Available in T3/T4/T5
  • Pre-Exit Source Material Available in T3/T4/T5
  • T3-T5 Material is 1-3 Years Pre-Dx (Cases)

Matching Factors:

  • Age at Randomization (5 year intervals)
  • Study Year of Blood Draw
  • Calendar Year of Blood Draw
  • Material Type

Match Ratio: 1:1

Match Technique: Frequency matching only non-cases as controls.

Additional Matching Comments: Matching factors pertaining to blood draw apply to both time points.


Analytes:

  • C6orf79 percent methylated
  • ERCC1 percent methylated
  • MGAT4C percent methylated
  • OPTN percent methylated
  • PRKCDBP percent methylated
  • methylated C6orf79
  • methylated ERCC1
  • methylated MGAT4C
  • methylated OPTN
  • methylated PRKCDBP
  • unmethylated C6orf79
  • unmethylated ERCC1
  • unmethylated MGAT4C
  • unmethylated OPTN
  • unmethylated PRKCDBP

Number of Cases: 300

Number of Controls: 300