Site: Lung
Inclusion Criteria:
- No Rare Cancer
 - No Prior History of Any Cancer
 - Whites and Blacks Only
 - No Reported Cancers in Controls
 - No Erroneous Reports of Cancer
 - Has Any Serum Available
 - Has .5ml Most Proximal Pre-DX Serum 2-7 Years Prior to DX
 - Has Genetic Consent
 - Has .4ug of DNA/Source (Eligible)
 - Individually Matched at a 1-1 Ratio
 - Limit to Matched Cases and Controls
 - Limit to Desired Smoking Groups (Selected)
 
Matching Factors:
- Gender
 - Race
 - Study Year of Draw
 - Time of Draw
 - Days in Study
 - Date of Birth +- 5 years
 - Date of Draw +- 6 months
 
Match Ratio: 1 to 1
Match Technique: Individual matching only non-cases as controls.
Analytes:
- 25-Hydroxyvitamin D2
 - 25-Hydroxyvitamin D3
 - 3-hydroxyanthranilic acid
 - 4-pyridoxic acid
 - Alpha Tocopherol
 - Anthranilic Acid
 - Any Amino Acid
 - Arginine R
 - Asymmetric dimethylarginine
 - Betaine
 - C-Reactive Protein
 - Choline
 - Cobalamin
 - Cotinine
 - Creatinine
 - Cystathionine
 - D-Neopterin
 - Dihydrokainic acid
 - Dimethylglycine
 - Gamma Tocopherol
 - Glycine
 - Homocysteine
 - Kynurenine
 - L-homoarginine
 - Methionine
 - Methionine sulfoxide
 - Methylmalonic acid
 - Nicotanic Acid
 - Nicotinamide
 - Plasma Total Cysteine
 - Protein
 - Pyridoxal 5'-Phosphate
 - Riboflavin
 - Sarcosine
 - Serine
 - Supplemental Folate
 - Symmetric dimethylarginine
 - Tryptophan
 - Valine
 - kynurenic acid
 - pyridoxal
 - quinolinic acid
 
Number of Cases: 450
Number of Controls: 450