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Trial Summary

About CDAS Project, PI, Publications: One-carbon metabolism and risk of lung cancer in a multi-cohort consortium

Datasets


Site: Lung

Inclusion Criteria:

  • No Rare Cancer
  • No Prior History of Any Cancer
  • Whites and Blacks Only
  • No Reported Cancers in Controls
  • No Erroneous Reports of Cancer
  • Has Any Serum Available
  • Has .5ml Most Proximal Pre-DX Serum 2-7 Years Prior to DX
  • Has Genetic Consent
  • Has .4ug of DNA/Source (Eligible)
  • Individually Matched at a 1-1 Ratio
  • Limit to Matched Cases and Controls
  • Limit to Desired Smoking Groups (Selected)

Matching Factors:

  • Gender
  • Race
  • Study Year of Draw
  • Time of Draw
  • Days in Study
  • Date of Birth +- 5 years
  • Date of Draw +- 6 months

Match Ratio: 1 to 1

Match Technique: Individual matching only non-cases as controls.


Analytes:

  • 25-Hydroxyvitamin D2
  • 25-Hydroxyvitamin D3
  • 3-hydroxyanthranilic acid
  • 4-pyridoxic acid
  • Alpha Tocopherol
  • Anthranilic Acid
  • Any Amino Acid
  • Arginine R
  • Asymmetric dimethylarginine
  • Betaine
  • C-Reactive Protein
  • Choline
  • Cobalamin
  • Cotinine
  • Creatinine
  • Cystathionine
  • D-Neopterin
  • Dihydrokainic acid
  • Dimethylglycine
  • Gamma Tocopherol
  • Glycine
  • Homocysteine
  • Kynurenine
  • L-homoarginine
  • Methionine
  • Methionine sulfoxide
  • Methylmalonic acid
  • Nicotanic Acid
  • Nicotinamide
  • Plasma Total Cysteine
  • Protein
  • Pyridoxal 5'-Phosphate
  • Riboflavin
  • Sarcosine
  • Serine
  • Supplemental Folate
  • Symmetric dimethylarginine
  • Tryptophan
  • Valine
  • kynurenic acid
  • pyridoxal
  • quinolinic acid

Number of Cases: 450

Number of Controls: 450