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Trial Summary

About CDAS Project, PI, Publications: Serum levels of per- and polyfluorinated substances and risks of non-Hodgkin lymphoma and thyroid cancer

Datasets


Site: Lymphoid

Inclusion Criteria:

  • No Rare Cancers
  • Remove Hema Cases not of Interest
  • Has Serum
  • Has 250ul Pre-DX Serum (Eligible)
  • Matched at a 2-1 Ratio for Thyroid and a 1-1 Ratio For Hematopoietic (Selected)

Matching Factors:

  • Gender
  • Race (W/B/O)
  • Center for Hema match
  • Grouped study year of material (T0, T1/T2, T4/T5)
  • Calendar Year of Draw +/- 1 year
  • Age at Draw +/- 3 years

Match Ratio: 2-1 for Thyroid; 1-1 for Hematopoietic

Match Technique: Frequency matching only non-cases as controls.

Additional Matching Comments: The Hema match was done first and then the thyroid match was done targeting controls selected for the hema cases.


Analytes:

  • PFDA
  • PFHpA
  • PFHpS
  • PFHxA
  • PFHxS
  • PFNA
  • PFOA
  • PFOS branched
  • PFOS linear
  • PFOS total
  • PFUnA

Number of Cases: 894

Number of Controls: 761