Site: Lymphoid

Inclusion Criteria:

• No Rare Cancers
• Remove Hema Cases not of Interest
• Has Serum
• Has 250ul Pre-DX Serum (Eligible)
• Matched at a 2-1 Ratio for Thyroid and a 1-1 Ratio For Hematopoietic (Selected)

Matching Factors:

• Gender
• Race (W/B/O)
• Center for Hema match
• Grouped study year of material (T0, T1/T2, T4/T5)
• Calendar Year of Draw +/- 1 year
• Age at Draw +/- 3 years

Match Ratio: 2-1 for Thyroid; 1-1 for Hematopoietic

Match Technique: Frequency matching only non-cases as controls.

Additional Matching Comments: The Hema match was done first and then the thyroid match was done targeting controls selected for the hema cases.

Analytes:

• PFDA
• PFHpA
• PFHpS
• PFHxA
• PFHxS
• PFNA
• PFOA
• PFOS branched
• PFOS linear
• PFOS total
• PFUnA

Number of Cases: 894

Number of Controls: 761

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