Site: Colon

Inclusion Criteria:

• No Rare Cancers
• No Prior History of Any Cancer
• No Specified Colon Comorbidities
• No Colorectal Cancers as non-first Diagnoses
• No T0 Adenomas in Colo/Inci. Aden. Controls
• With Pre-Exit Serum

Matching Factors:

• Gender
• Age at Randomization (5 year intervals)
• Race (3 levels)
• Geographic Region (latitudinal)
• Study Year of Draw + Calendar Year of Draw
• Month of Draw
• Time of Day of Draw (am/pm)

Match Ratio: 1:1

Match Technique: Frequency matching only non-cases as controls.

Additional Matching Comments: Year/month/time of draw were loosened, as needed, to complete matching. No matching was performed for recurrent adenoma cases.

Analytes:

• 25-Hydroxyvitamin D
• N-TACT Parathyroid Hormone

Number of Cases: 750 colorectal; 753 incident adenoma; 755 recurrent adenoma

Number of Controls: 751 colorectal; 755 incident adenoma; 755 recurrent adenoma

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