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Trial Summary

About CDAS Project, PI, Publications: Inflammation markers and risk of endometrial and ovarian cancer

Datasets


Site: Endometrial

Inclusion Criteria:

  • Females in Intervention Arm
  • No Rare Cancers
  • No Prior History of Any Cancer
  • No Confirmed or Reported Cancers in Controls
  • No Hysterectomy
  • No Endometrial Cancers that are 2nd, reported, or unconfirmable
  • Has Any Serum Available
  • Has Pre-dx Serum Available
  • Frequency Matched at a 1-1 Ratio

Matching Factors:

  • Fiscal Year of Randomization
  • Age at Randomization (5 year intervals)
  • Race (White/Non-White)
  • Study Year of Blood Draw
  • Study Year of Exit

Match Ratio: 1 to 1

Match Technique: Frequency matching only non-cases as controls.


Analytes:

  • Adiponectin
  • Adipsin
  • B-Cell Attracting Chemokine 1
  • Basic Fibroblast Growth Factor
  • C-Reactive Protein
  • Chemokine (C-C Motif) Ligand 13
  • Chemokine (C-C Motif) Ligand 19
  • Chemokine (C-C Motif) Ligand 2
  • Chemokine (C-C Motif) Ligand 20
  • Chemokine (C-C Motif) Ligand 21
  • Chemokine (C-C Motif) Ligand 22
  • Chemokine (C-C Motif) Ligand 27
  • Chemokine (C-C Motif) Ligand 8
  • Chemokine (C-X-C Motif) Ligand 1
  • Chemokine (C-X-C Motif) Ligand 10
  • Chemokine (C-X-C Motif) Ligand 11
  • Chemokine (C-X-C Motif) Ligand 12
  • Chemokine (C-X-C Motif) Ligand 5
  • Chemokine (C-X-C Motif) Ligand 6
  • Chemokine (C-X-C Motif) Ligand 9
  • Eotaxin
  • Eotaxin-2
  • Epidermal Growth Factor
  • Estradiol
  • Granulocyte-Colony Stimulating Factor
  • Interleukin 1
  • Interleukin 1 Receptor Antagonist
  • Interleukin 16
  • Interleukin 29
  • Interleukin 33
  • Interleukin 7
  • Interleukin 8
  • Lipocalin-2
  • Macrophage Inflammatory Protein 1 delta
  • Macrophage inflammatory protein 1 beta
  • Plasminogen activator inhibitor-1
  • Resistin
  • Serum Amyloid A
  • Serum Amyloid P
  • Soluble Epidermal Growth Factor Receptor
  • Soluble Interleukin 4 Receptor
  • Soluble Interleukin 6 Receptor
  • Soluble Interleukin 6 beta
  • Soluble Tumor Necrosis Factor Receptor I
  • Soluble Tumor Necrosis Factor Receptor II
  • Stem Cell Factor
  • Thrombopoietin
  • Thymic Stromal Lymphopoietin
  • Thymus and Activation Regulated Chemokine
  • Transforming Growth Factor Alpha
  • Transforming Growth Factor Beta 1
  • Tumor Necrosis Factor Alpha 1
  • Tumor Necrosis Factor Beta
  • Tumor Necrosis Factor Receptor Superfamily, Member 10
  • Vascular Endothelial Growth Factor
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3

Number of Cases: 284

Number of Controls: 284




Site: Ovary

Inclusion Criteria:

  • Females in Intervention Arm
  • No Rare Cancers in Controls
  • No Controls with Oophorectomies
  • 2+ Years Pre-Diagnostic Specimen Available

Matching Factors:

  • Age at Randomization (5 year intervals)
  • Race
  • Study Year of Blood Draw
  • Year of Blood Draw
  • Season of Blood Draw
  • Time of Blood Draw (am/pm)

Match Ratio: 1 to 1

Match Technique: Case cohort with controls matched to cases.

Additional Matching Comments: One cell had no matched controls; the case was kept.


Analytes:

  • Amylin
  • Basic Fibroblast Growth Factor
  • C-Peptide
  • C-Reactive Protein
  • Chemokine (C-C Motif) Ligand 2
  • Chemokine (C-C Motif) Ligand 22
  • Chemokine (C-X-C Motif) Ligand 1
  • Chemokine (C-X-C Motif) Ligand 10
  • Chemokine (C-X3-C Motif) Ligand 1
  • Chemokine Ligand 7
  • Eotaxin
  • Epidermal Growth Factor
  • Fms-related tyrosine kinase 3 ligand
  • Gastric inhibitory polypeptide
  • Glucagon
  • Glucagon-like peptide-1
  • Granulocyte-Colony Stimulating Factor
  • Granulocyte-Macrophage Colony Stimulating Factor
  • Insulin
  • Interferon alpha-2
  • Interferon-gamma
  • Interleukin 1
  • Interleukin 1 Receptor Antagonist
  • Interleukin 1 alpha
  • Interleukin 1 beta
  • Interleukin 10
  • Interleukin 12 p40
  • Interleukin 12 p70
  • Interleukin 15
  • Interleukin 17
  • Interleukin 2
  • Interleukin 3
  • Interleukin 4
  • Interleukin 5
  • Interleukin 6
  • Interleukin 7
  • Interleukin 8
  • Leptin
  • Macrophage Inflammatory Protein 1 alpha
  • Macrophage inflammatory protein 1 beta
  • Pancreatic Polipeptide
  • Pancreatic Polipeptide YY
  • Soluble Epidermal Growth Factor Receptor
  • Soluble Interleukin 1 Receptor Type 1
  • Soluble Interleukin 2 Receptor Alpha
  • Soluble Interleukin 4 Receptor
  • Soluble Interleukin 6 Receptor
  • Soluble Interleukin 6 beta
  • Soluble Receptor for Advanced Glycation Endproducts
  • Soluble Tumor Necrosis Factor Receptor I
  • Soluble Tumor Necrosis Factor Receptor II
  • Transforming Growth Factor Alpha
  • Tumor Necrosis Factor Alpha 1
  • Tumor Necrosis Factor Beta
  • Tumor Necrosis Factor Receptor Superfamily, Member 5
  • Tumor Necrosis Factor Receptor Superfamily, Member 8
  • Vascular Endothelial Growth Factor
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3

Number of Cases: 150

Number of Controls: 169