Site: Renal

Inclusion Criteria:

• No Prior History of Any Cancer
• White, Non-Hispanic
• No Rare Cancers in Controls
• Not From Hawaii Center
• Buffy Coat/DNA Ext. from Buffy/Pending Extraction from Buffy
• Pre-DX Material
• Rematched

Matching Factors:

• Gender
• Age at Randomization (5 year intervals)
• Fiscal Year of Entry
• Material Study Year
• Time on Study

Match Ratio: 2-1 control to case ratio

Match Technique: Frequency matching with replacement and cases as controls (Incidence Density)

Additional Matching Comments: Cases were intially matched to all controls and then a rematch was done to replace non-gwas controls with gwas controls.

Analytes:

• Methylation 1A
• Methylation 1B
• Methylation 1C
• Methylation 2A
• Methylation 2B
• Methylation 2C
• Methylation 3A
• Methylation 3B
• Methylation 3C
• Methylation 4A
• Methylation 4B
• Methylation 4C

Number of Cases: 233

Number of Controls: 465

---