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Trial Summary

About CDAS Project, PI, Publications: Serum Estrogens and Subsequent Risk of Prostate Cancer

Datasets


Site: Prostate

Inclusion Criteria:

  • All I-Arm Men
  • No Prior History of Prostate Cancer
  • White, Non-Hispanic
  • Not From Hawaii Center
  • No Rare Cancers in Controls
  • Perfect Serum at T0 or .5+ ml child or in 2008-256,2009-555, or 2009-565
  • Incident (Cases Only)
  • In Prostate BPC3 Biochemical
  • In Final Population (Original Selection Line)
  • Has .5ml of Serum Available
  • Updated Advanced Case or Updated Control
  • Updated Case with Age at Dx <= 70 or Updated Control
  • Exclude All Rare Cancers
  • No Controls With no Results
  • Matched Cases at a 1-1 Ratio

Matching Factors:

  • Age at Randomization (5 year intervals)
  • Original Draw Year

Match Ratio: 1 to 1

Match Technique: Frequency matching only non-cases as controls.


Analytes:

  • 16-Epiestriol
  • 16-Ketoestradiol
  • 16Alpha-Hydroxyestrone
  • 17-Epiestriol
  • 2-Hydroxyestradiol
  • 2-Hydroxyestrone
  • 2-Hydroxyestrone-3-Methyl Ether
  • 2-Methoxyestradiol
  • 2-Methoxyestrone
  • 4-Hydroxyestrone
  • 4-Methoxyestradiol
  • 4-Methoxyestrone
  • Estradiol
  • Estriol
  • Estrone

Number of Cases: 195

Number of Controls: 195