Site: Ovary
Inclusion Criteria:
- Females
- No Prior History of Any Cancer
- No Report of Bilateral Oophorectomy
- Exclude LMPs and Reported Cancers
Matching Factors:
- Age at Serum Draw (5 years)
- Year of Serum Draw
Match Ratio: 4:1 for general controls, 2:1 for controls who ever had an elevated CA-125, and 2:1 for controls who have a family history of breast or ovarian cancer
Match Technique: Frequency matching only non-cases as controls.
Analytes:
- Apolipoprotein A-I
- Beta-2-microglobulin
- Cancer Antigen 125
- Cancer Antigen 15-3
- Cancer Antigen 19-9
- Cancer Antigen 72-4
- Connective Tissue-Activating Peptide III
- Eotaxin
- Epidermal Growth Factor Receptor
- Hepcidin-25
- Human Epididymis Protein 4
- Insulin-like Growth Factor 2
- Insulin-like Growth Factor Binding Protein 2
- Inter-alpha-trypsin inhibitor heavy chain H4
- Kallikrein-6
- Leptin
- Macrophage Migration Inhibitory Factor
- Matrix Metalloproteinase-3
- Matrix Metalloproteinase-7
- Mesothelin
- Osteopontin
- Prolactin
- Secretory Leukocyte Protease Inhibitor
- Soluble Vascular Cell Adhesion Molecule
- Spondin 2
- Transferrin
- Transthyretin
- V-set domain-containing T-cell activation inhibitor 1
Number of Cases: 119
Number of Controls: 952