Site: Lung

Inclusion Criteria:

• Prior History of Any Cancer
• No (non-Lung) Cancer During Trial
• Valid Smoking History

Matching Factors:

• Gender
• Smoking History
• Packyears
• Years since quitting smoking
• Year of Randomization (2 year intervals)

Match Ratio: 3 to 1 for non-smokers, 1 to 1 for former/current smokers

Match Technique: Frequency matching with replacement and cases as controls (Incidence Density)

Analytes:

• C-Reactive Protein
• Heat Shock Proteins
• Immunoglobulin A
• Immunoglobulin G
• Neopterin

Number of Cases: 593

Number of Controls: 659

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