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Browse Lab Results > 2005-0011

Trial Summary

About CDAS Project, PI, Publications: Inflammation regulation: Gene variants and inflammatory markers in colorectal neoplasia

Datasets

Site: Colorectal

Inclusion Criteria:

  • All I-Arm
  • T0 Negative or Colon Negative
  • With Signature
  • DNA/Source Available
  • No Previous Colon Disease
  • Adequate T3/5 Screen
  • T5 FSG Before 10/01/2003
  • 5 Vials of T0 Serum
  • Selected Population Genotype Population
  • No Cancer Prior to T3/5 Screen
  • Has 2 Vials of T0 Serum
  • No Confirmed Cancer (Selected Biochemical Population)

Matching Factors:

  • Age at Randomization (5 year intervals)
  • Race
  • Fiscal Year of Randomization
  • Gender
  • Protocol (T3/T5)

Match Ratio: 1 to 1

Match Technique: Frequency matching only non-cases as controls.

Additional Matching Comments: Matching was done on the genetic component of this study. The biochemical portion is the subset of that match with available serum.

Analytes:

  • C-Reactive Protein
  • Ferritin
  • Iron
  • SE Fat Percent
  • Total Iron Binding Capacity
  • Unsaturated Iron Binding Capacity

Number of Cases: 356

Number of Controls: 396


Site: Colorectal

Inclusion Criteria:

  • All I-Arm
  • agg_left in (0,1) [potential cases and controls]
  • rnddate < 10/99
  • Successful FSG
  • No Previous Colon Disease
  • Has T0 or T3 Blood
  • Has Sig1
  • Selected for nested case/control

Matching Factors:

  • Gender
  • Race

Match Ratio: 1 to 1

Match Technique: Frequency matched, non-cases as controls only

Additional Matching Comments: Prevalent advanced adenoma cases were matched to non-cases at a 1-1 ratio without replacement

Analytes:

  • Insulin-like Growth Factor 1
  • Insulin-like Growth Factor 2
  • Insulin-like Growth Factor Binding Protein 3

Number of Cases: 770

Number of Controls: 777