Site: Lymphoid

Inclusion Criteria:

• No Rare Cancers in Controls
• Serum Available
• Pre-Diagnostic Serum Available
• Pre-Diagnostic Serum Available in Preferred Study Year

Matching Factors:

• Gender
• Race (W/B/O)
• Study year of draw
• Age at draw (+/- 2 years)
• Date of draw (+/- 365 days)
• Number of thaws

Match Ratio: 1:1

Match Technique: Individual matching only non-cases as controls.

Additional Matching Comments: Study year and date of draw loosened, where needed, to complete matching. One case diagnosed very late was matched to a control with slightly less followup.

Analytes:

• Angiopoietin-2
• B-Cell Attracting Chemokine 1
• Basic Fibroblast Growth Factor
• Basic fibroblast growth factor alpha 17
• Bone morphogenetic protein
• CD27
• CD30
• Chemokine (C-C Motif) Ligand 13
• Chemokine (C-C Motif) Ligand 2
• Chemokine (C-C Motif) Ligand 21
• Chemokine (C-C Motif) Ligand 22
• Chemokine (C-C Motif) Ligand 27
• Chemokine (C-C Motif) Ligand 8
• Chemokine (C-X-C Motif) Ligand 1
• Chemokine (C-X-C Motif) Ligand 10
• Chemokine (C-X-C Motif) Ligand 12
• Chemokine (C-X-C Motif) Ligand 5
• Endoglin
• Endothelin 1
• Eotaxin
• Eotaxin-2
• Epidermal Growth Factor
• Epidermal growth factor alpha 17
• Follistatin
• Granulocyte-Colony Stimulating Factor
• Granulocyte-Colony Stimulating Factor alpha 17
• Heparin-binding EGF-like growth factor
• Heparin-binding growth factor 1
• Hepatocyte Growth Factor
• Interleukin 1 Receptor Antagonist
• Interleukin 16
• Interleukin 3
• Interleukin 33
• Interleukin 7
• Interleukin 8
• Interleukin 8 alpha 17
• Leptin
• Macrophage Inflammatory Protein 1 delta
• Macrophage inflammatory protein 1 beta
• Placental Growth Factor
• Stem Cell Factor
• Thrombopoietin
• Thymic Stromal Lymphopoietin
• Thymus and Activation Regulated Chemokine
• Transforming Growth Factor Alpha
• Tumor Necrosis Factor Alpha 1
• Tumor Necrosis Factor Beta
• Tumor Necrosis Factor Receptor Superfamily, Member 10
• Vascular Endothelial Growth Factor
• Vascular endothelial growth factor A
• Vascular endothelial growth factor C
• Vascular endothelial growth factor D

Number of Cases: 764

Number of Controls: 256

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Site: Lymphoid

Inclusion Criteria:

• No Cancer Prior to Randomization
• No Rare Cancer
• With Consent (ESC1)
• With Perfect T0 Serum
• Selected Subjects
• Adjustments for Batching

Matching Factors:

• Age at Randomization (5 year intervals)
• Race
• Gender
• Study Center
• Entry Season/Year
• Time of Blood Draw (am/pm)
• Exit Date

Match Ratio: 1 to 1

Match Technique: Individual matching only non-cases as controls.

Analytes:

• Amylin
• B-Cell Attracting Chemokine 1
• Basic Fibroblast Growth Factor
• C-Peptide
• Chemokine (C-C Motif) Ligand 13
• Chemokine (C-C Motif) Ligand 19
• Chemokine (C-C Motif) Ligand 2
• Chemokine (C-C Motif) Ligand 20
• Chemokine (C-C Motif) Ligand 21
• Chemokine (C-C Motif) Ligand 22
• Chemokine (C-C Motif) Ligand 27
• Chemokine (C-C Motif) Ligand 8
• Chemokine (C-X-C Motif) Ligand 1
• Chemokine (C-X-C Motif) Ligand 10
• Chemokine (C-X-C Motif) Ligand 11
• Chemokine (C-X-C Motif) Ligand 12
• Chemokine (C-X-C Motif) Ligand 5
• Chemokine (C-X-C Motif) Ligand 6
• Chemokine (C-X-C Motif) Ligand 9
• Chemokine (C-X3-C Motif) Ligand 1
• Chemokine Ligand 7
• Eotaxin
• Eotaxin-2
• Epidermal Growth Factor
• Fms-related tyrosine kinase 3 ligand
• Gastric inhibitory polypeptide
• Glucagon
• Glucagon-like peptide-1
• Granulocyte-Colony Stimulating Factor
• Granulocyte-Macrophage Colony Stimulating Factor
• Insulin
• Interferon alpha-2
• Interferon-gamma
• Interleukin 1
• Interleukin 1 Receptor Antagonist
• Interleukin 1 alpha
• Interleukin 1 beta
• Interleukin 10
• Interleukin 11
• Interleukin 12 p40
• Interleukin 12 p70
• Interleukin 15
• Interleukin 16
• Interleukin 17
• Interleukin 2
• Interleukin 29
• Interleukin 3
• Interleukin 33
• Interleukin 4
• Interleukin 5
• Interleukin 6
• Interleukin 7
• Interleukin 8
• Leptin
• Leukemia Inhibitory Factor
• Macrophage Inflammatory Protein 1 alpha
• Macrophage Inflammatory Protein 1 delta
• Macrophage inflammatory protein 1 beta
• Pancreatic Polipeptide
• Pancreatic Polipeptide YY
• Soluble Epidermal Growth Factor Receptor
• Soluble Interleukin 1 Receptor Type 1
• Soluble Interleukin 2 Receptor Alpha
• Soluble Interleukin 4 Receptor
• Soluble Interleukin 6 Receptor
• Soluble Interleukin 6 beta
• Soluble Receptor for Advanced Glycation Endproducts
• Soluble Tumor Necrosis Factor Receptor I
• Soluble Tumor Necrosis Factor Receptor II
• Stem Cell Factor
• Thrombopoietin
• Thymic Stromal Lymphopoietin
• Thymus and Activation Regulated Chemokine
• Transforming Growth Factor Alpha
• Tumor Necrosis Factor Alpha 1
• Tumor Necrosis Factor Beta
• Tumor Necrosis Factor Receptor Superfamily, Member 10
• Tumor Necrosis Factor Receptor Superfamily, Member 5
• Tumor Necrosis Factor Receptor Superfamily, Member 8
• Vascular Endothelial Growth Factor
• Vascular endothelial growth factor receptor 1
• Vascular endothelial growth factor receptor 2
• Vascular endothelial growth factor receptor 3

Number of Cases: 307

Number of Controls: 307

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