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Approved PLCO Projects

Here you can browse the complete list of projects for PLCO whose requests for data/biospecimens were approved.

Filter results of approved projects table below

Approved Projects
Name Principal Investigator Institution Study Date Approved Project ID
Validation of CA-125 Kinetic Models for Early Ovarian Cancer Detection Using Machine Learning Fahad Kiani CrisPRO.ai PLCO Feb 23, 2026 PLCO-2010
Plasma proteomics markers for risk prediction of incident lung cancer Charles Swanton Francis Crick Institute PLCO Feb 19, 2026 2025-0069
DNA methylation and dietary sodium intake Jeong Yun (John) Yang Columbia University Irving Medical Center PLCO Feb 17, 2026 PLCO-2023
Dietary Advanced Glycation End-Products (dAGE) and Prostate Cancer Susan Steck University of South Carolina PLCO Feb 13, 2026 PLCO-2021
Computational Prediction of Gene Expression and Clinical Outcomes from Digital Pathology Images Mingyao Li University of Pennsylvania PLCO Feb 13, 2026 PLCOI-2022
Validation of a Morphology-Based Risk Taxonomy (Favorable, Borderline, Unfavorable Histology) for Prostate Cancer Using PLCO Trial Data Enrico Munari University Hospital Trust Verona PLCO Feb 4, 2026 PLCOI-2019
Bone Marrow Extracellular Matrix Gene Expression Analysis for Cancer Prognosis and Bone Metastasis Prediction: An 82-Gene Panel Study Using PLCO Trial Data Shelly Peyton Trustees of Tufts College PLCO Feb 4, 2026 PLCO-2011
Causal predictive modeling of survival of Breast cancer: A comparative study with machine learning, traditional survival modeling methods, and causal survival models Hansapani Rodrigo University of Texas Rio Grande Valley PLCO Feb 4, 2026 PLCO-2015
Epstein-Barr virus-associated neo-antigens in advanced prostate cancer Denong Wang SRI International PLCO Feb 2, 2026 2025-0062
Predicting eligibility for lung cancer screening Robert Volk University of Texas MD Anderson Cancer Center PLCO Jan 26, 2026 PLCO-2018
Impact of a secondary biomarker on time-to-event risk prediction of prostate cancer mortality in a screening cohort Kristian Stensland The University of Michigan PLCO Jan 26, 2026 PLCO-2012
Association between microplastic concentration in whole blood and risk of colorectal cancer in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial Rena Jones National Cancer Institute PLCO Jan 26, 2026 2025-0059
Incidence Rates of Lung and Bladder Cancer According to Smoking Status and Tumor Subtype: An Analysis of Absolute Risk in Never Smokers Sarina Murray National Cancer Institute PLCO Jan 16, 2026 PLCO-2017
PLCO Germline Materials for Integrated Whole-Genome Discovery of Lung Cancer Susceptibility with the Sherlock-Lung Study Maria Teresa Landi National Cancer Institute, National Institutes of Health PLCO Jan 15, 2026 PLCO-2016
Evaluation of medical conditions associated with oral tongue cancer Anil Chaturvedi National Cancer Institute PLCO Jan 9, 2026 PLCO-2013
Causal predictive modeling of survival of Breast cancer: A comparative study with machine learning, traditional survival modeling methods along and causal survival models Malinda Iluppangama Loyola University Maryland PLCO Jan 8, 2026 PLCO-2009
PLCO Digital Pathology Whole-Slide Images for Multimodal AI Modeling and Validation Yuming Jiang Wake Forest University Health Sciences PLCO Jan 7, 2026 PLCOI-2007
PLCO Colorectal Cohort Tables for Outcome Labeling and WSI Linkage to Support Risk Modeling Yuming Jiang Wake Forest University Health Sciences PLCO Jan 7, 2026 PLCO-2006
Developing a risk calculator for the early detection of prostate cancer Visalini Nair-Shalliker The Daffodil Centre, The University Sydney, and Cancer Council,NSW PLCO Dec 22, 2025 PLCO-1993
Learning about the effectiveness of lung cancer screening in real-world target populations Sarah Robertson Dartmouth College PLCO Dec 22, 2025 PLCO-2005