Site: Colorectal

Inclusion Criteria:

• DQX and DHQ
• No Prior History of Any Cancer
• No Rare Cancers in Controls
• No Colon Diseases

Matching Factors:

• Race
• Gender
• Age at Randomization (5 year intervals)
• Fiscal Year of Randomization
• Season of Blood Draw

Match Ratio: 1:1

Match Technique: Frequency matching with replacement and cases as controls (Incidence Density)

Additional Matching Comments: Frequency controls were rematched individually to GWAS subjects with additional concern to smoking history.

Analytes:

• Metabolomics

Number of Cases: 253

Number of Controls: 223

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