Site: Ovary

Inclusion Criteria:

• Females
• No Prior History of Any Cancer
• No Report of Bilateral Oophorectomy
• Exclude LMPs and Reported Cancers

Matching Factors:

• Age at Serum Draw (5 years)
• Year of Serum Draw

Match Ratio: 4:1 for general controls, 2:1 for controls who ever had an elevated CA-125, and 2:1 for controls who have a family history of breast or ovarian cancer

Match Technique: Frequency matching only non-cases as controls.

Analytes:

• Apolipoprotein A-I
• Beta-2-microglobulin
• Cancer Antigen 125
• Cancer Antigen 15-3
• Cancer Antigen 19-9
• Cancer Antigen 72-4
• Connective Tissue-Activating Peptide III
• Eotaxin
• Epidermal Growth Factor Receptor
• Hepcidin-25
• Human Epididymis Protein 4
• Insulin-like Growth Factor 2
• Insulin-like Growth Factor Binding Protein 2
• Inter-alpha-trypsin inhibitor heavy chain H4
• Kallikrein-6
• Leptin
• Macrophage Migration Inhibitory Factor
• Matrix Metalloproteinase-3
• Matrix Metalloproteinase-7
• Mesothelin
• Osteopontin
• Prolactin
• Secretory Leukocyte Protease Inhibitor
• Soluble Vascular Cell Adhesion Molecule
• Spondin 2
• Transferrin
• Transthyretin
• V-set domain-containing T-cell activation inhibitor 1

Number of Cases: 119

Number of Controls: 952

---