Site: Endometrial

Inclusion Criteria:

• No Prior History of Any Cancer
• T0 Serum Available
• No Uncontrolled Thaws
• Female
• Confirmed Post Menopausal
• No Bilateral Oophorectomy at Baseline
• No Hysterectomy at Baseline

Matching Factors:

• Gender
• Race
• Age at Selection (+/- 1 year)
• Month of Blood Draw (+/- 30 days)

Match Ratio: 1 to 1

Match Technique: Individual matching with replacement and cases as controls.

Analytes:

• 25-Hydroxyvitamin D

Number of Cases: 155

Number of Controls: 155

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Site: Lymphoid

Inclusion Criteria:

• Has Signature
• No Baseline Cancer
• Has 2 Perfect T0 Serum Vials
• Not Prevalent Cancer

Matching Factors:

• Age at Randomization (5 year intervals)
• Race
• Gender
• Season of Blood Draw
• Study Year of Exit

Match Ratio: 1 to 1

Match Technique: Frequency matching with replacement and cases as controls (Incidence Density)

Analytes:

• 25-Hydroxyvitamin D

Number of Cases: 297

Number of Controls: 296

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Site: Ovary

Inclusion Criteria:

• No Prior History of Any Cancer
• T0 Serum Available
• No Uncontrolled Thaws
• Female
• Confirmed Post Menopausal
• No Bilateral Oophorectomy at Baseline

Matching Factors:

• Gender
• Race
• Age at Selection (+/- 1 year)
• Month of Blood Draw (+/- 30 days)

Match Ratio: 1 to 1

Match Technique: Individual matching with replacement and cases as controls.

Analytes:

• 25-Hydroxyvitamin D

Number of Cases: 79

Number of Controls: 79

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Site: Renal

Inclusion Criteria:

• No Prior History of Any Cancer
• T0 Serum Available
• No Uncontrolled Thaws

Matching Factors:

• Gender
• Race
• Age at Selection (+/- 1 year)
• Month of Blood Draw (+/- 30 days)

Match Ratio: 1 to 1

Match Technique: Individual matching with replacement and cases as controls.

Analytes:

• 25-Hydroxyvitamin D

Number of Cases: 163

Number of Controls: 163

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Site: Upper GI

Inclusion Criteria:

• No Prior History of Any Cancer
• T0 Serum Available
• No Uncontrolled Thaws

Matching Factors:

• Gender
• Race
• Age at Selection (+/- 1 year)
• Month of Blood Draw (+/- 30 days)

Match Ratio: 1 to 1

Match Technique: Individual matching with replacement and cases as controls.

Analytes:

• 25-Hydroxyvitamin D

Number of Cases: 102

Number of Controls: 100

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