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Trial Summary

About CDAS Project, PI, Publications: Serum 25-hydroxyvitamin D, dietary vitamin D and non-Hodgkin Lymphoma: a Nested Case Control Study in the PLCO Trial

Datasets


Site: Endometrial

Inclusion Criteria:

  • No Prior History of Any Cancer
  • T0 Serum Available
  • No Uncontrolled Thaws
  • Female
  • Confirmed Post Menopausal
  • No Bilateral Oophorectomy at Baseline
  • No Hysterectomy at Baseline

Matching Factors:

  • Gender
  • Race
  • Age at Selection (+/- 1 year)
  • Month of Blood Draw (+/- 30 days)

Match Ratio: 1 to 1

Match Technique: Individual matching with replacement and cases as controls.


Analytes:

  • 25-Hydroxyvitamin D

Number of Cases: 155

Number of Controls: 155




Site: Lymphoid

Inclusion Criteria:

  • Has Signature
  • No Baseline Cancer
  • Has 2 Perfect T0 Serum Vials
  • Not Prevalent Cancer

Matching Factors:

  • Age at Randomization (5 year intervals)
  • Race
  • Gender
  • Season of Blood Draw
  • Study Year of Exit

Match Ratio: 1 to 1

Match Technique: Frequency matching with replacement and cases as controls (Incidence Density)


Analytes:

  • 25-Hydroxyvitamin D

Number of Cases: 297

Number of Controls: 296




Site: Ovary

Inclusion Criteria:

  • No Prior History of Any Cancer
  • T0 Serum Available
  • No Uncontrolled Thaws
  • Female
  • Confirmed Post Menopausal
  • No Bilateral Oophorectomy at Baseline

Matching Factors:

  • Gender
  • Race
  • Age at Selection (+/- 1 year)
  • Month of Blood Draw (+/- 30 days)

Match Ratio: 1 to 1

Match Technique: Individual matching with replacement and cases as controls.


Analytes:

  • 25-Hydroxyvitamin D

Number of Cases: 79

Number of Controls: 79




Site: Renal

Inclusion Criteria:

  • No Prior History of Any Cancer
  • T0 Serum Available
  • No Uncontrolled Thaws

Matching Factors:

  • Gender
  • Race
  • Age at Selection (+/- 1 year)
  • Month of Blood Draw (+/- 30 days)

Match Ratio: 1 to 1

Match Technique: Individual matching with replacement and cases as controls.


Analytes:

  • 25-Hydroxyvitamin D

Number of Cases: 163

Number of Controls: 163




Site: Upper GI

Inclusion Criteria:

  • No Prior History of Any Cancer
  • T0 Serum Available
  • No Uncontrolled Thaws

Matching Factors:

  • Gender
  • Race
  • Age at Selection (+/- 1 year)
  • Month of Blood Draw (+/- 30 days)

Match Ratio: 1 to 1

Match Technique: Individual matching with replacement and cases as controls.


Analytes:

  • 25-Hydroxyvitamin D

Number of Cases: 102

Number of Controls: 100