Results of Study
- Primary Results
Reduced lung-cancer mortality with low-dose computed tomographic screening.
National Lung Screening Trial Research Team, Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, Gareen IF, Gatsonis C, Marcus PM, Sicks JD
N. Engl. J. Med. 2011 Aug; Volume 365 (Issue 5): Pages 395-409 PUBMED
- Baseline Demographics
Baseline characteristics of participants in the randomized national lung screening trial.
National Lung Screening Trial Research Team, Aberle DR, Adams AM, Berg CD, Clapp JD, Clingan KL, Gareen IF, Lynch DA, Marcus PM, Pinsky PF
J. Natl. Cancer Inst. 2010 Dec; Volume 102 (Issue 23): Pages 1771-9 PUBMED
- Screening Results from First Round (T0)
Results of initial low-dose computed tomographic screening for lung cancer.
National Lung Screening Trial Research Team, Church TR, Black WC, Aberle DR, Berg CD, Clingan KL, Duan F, Fagerstrom RM, Gareen IF, Gierada DS, Jones GC, Mahon I, Marcus PM, Sicks JD, Jain A, Baum S
N. Engl. J. Med. 2013 May; Volume 368 (Issue 21): Pages 1980-91 PUBMED
- Screening Results from Second and Third Rounds (T1-T2)
Results of the two incidence screenings in the National Lung Screening Trial.
Aberle DR, DeMello S, Berg CD, Black WC, Brewer B, Church TR, Clingan KL, Duan F, Fagerstrom RM, Gareen IF, Gatsonis CA, Gierada DS, Jain A, Jones GC, Mahon I, Marcus PM, Rathmell JM, Sicks J, National Lung Screening Trial Research Team
N. Engl. J. Med. 2013 Sep; Volume 369 (Issue 10): Pages 920-31 PUBMED
Design / Process
- Overview and Design
The National Lung Screening Trial: overview and study design.
National Lung Screening Trial Research Team, Aberle DR, Berg CD, Black WC, Church TR, Fagerstrom RM, Galen B, Gareen IF, Gatsonis C, Goldin J, Gohagan JK, Hillman B, Jaffe C, Kramer BS, Lynch D, Marcus PM, Schnall M, Sullivan DC, Sullivan D, Zylak CJ
Radiology. 2011 Jan; Volume 258 (Issue 1): Pages 243-53 PUBMED
Recruitment methods employed in the National Lung Screening Trial.
Marcus PM, Lenz S, Sammons D, Black W, Garg K
J Med Screen. 2012 Jun; Volume 19 (Issue 2): Pages 94-102 PUBMED
- Endpoint Verification Process
The National Lung Screening Trial's Endpoint Verification Process: determining the cause of death.
Marcus PM, Gareen IF, Miller AB, Rosenbaum J, Keating K, Aberle DR, Berg CD
Contemp Clin Trials. 2011 Nov; Volume 32 (Issue 6): Pages 834-40 PUBMED
- ACRIN Image Quality Control
Description and implementation of a quality control program in an imaging-based clinical trial.
Cagnon CH, Cody DD, McNitt-Gray MF, Seibert JA, Judy PF, Aberle DR
Acad Radiol. 2006 Nov; Volume 13 (Issue 11): Pages 1431-41 PUBMED
- LSS CT Quality Assurance
CT quality assurance in the lung screening study component of the National Lung Screening Trial: implications for multicenter imaging trials.
Gierada DS, Garg K, Nath H, Strollo DC, Fagerstrom RM, Ford MB
AJR Am J Roentgenol. 2009 Aug; Volume 193 (Issue 2): Pages 419-24 PUBMED
- LSS Manual of Operations and Procedures (MOOP)
The LSS MOOP (PDF - 6.4 MB) summarizes procedures used by the LSS group of NLST Screening Centers.
- ACRIN Protocol
The ACRIN protocol summarizes procedures used by the ACRIN group of NLST Screening Centers. You may contact ACRIN for more information.
Related Web Sites
- DSMB announcement of NLST Results
- NCI NLST Web site
- ACRIN Web site
ACRIN Protocol Summary Table (You may contact ACRIN and ask about protocol #6654 for more information.)