BMI, weight change, and site-specific cancer incidence in PLCO
1. Examine the associations of BMI in young adulthood (approximately ages 17-21), in middle-to-older adulthood (approximately age 50), and at baseline with the risks of total and site-specific cancers.
2. Examine associations for BMI change between young adulthood and middle-to-older adulthood on the risks of total and site-specific cancers.
Site-specific cancers include:
By site: female breast, endometrial, ovarian, liver, kidney, thyroid, pancreatic, non-Hodgkin lymphoma, multiple myeloma, leukemia, colorectal, lung, and prostate
By site and histology: esophageal adenocarcinoma, gastric cardia
Wen-Yi Huang, NCI
Patricia Hartge, NCI
Amy Berrington de Gonzalez, NCI
Steven Moore, NCI
Philip Rosenberg, NCI
-
Prospective investigation of body mass index, colorectal adenoma, and colorectal cancer in the prostate, lung, colorectal, and ovarian cancer screening trial.
Kitahara CM, Berndt SI, de González AB, Coleman HG, Schoen RE, Hayes RB, Huang WY
J. Clin. Oncol. 2013 Jul; Volume 31 (Issue 19): Pages 2450-9 PUBMED