The Lung Screening Study
The Lung Screening Study (LSS) was a pilot study designed to assess the feasibility of conducting a large scale randomized controlled trial (RCT) of low radiation dose spiral computed tomography (LDCT) versus chest X-ray (CXR) for lung cancer screening. During the fall of 2000, six PLCO screening centers recruited a total of 3,318 heavy or long-term smokers who were not participants in the PLCO trial and randomized them to receive either a screening LDCT scan (1,660 participants) or screening posteroanterior view chest radiograph (CXR) [1,658 participants].
The results of the LSS demonstrated convincingly the feasibility of an RCT of LDCT scanning in the United States.
This website is organized into several sections as follows.
- Learn About
This describes the trial, explaining how and what data were collected. The main findings of the trial can be found here.
This page has detailed documentation of the datasets available on this website, including data dictionaries.
- Approved Projects
Search through approved projects that used this trial's data.
Search through published articles on this trial's data.
Begin a new Project
Learn how to access the available datasets.
- Submit a project proposal.
- Brief review by NCI.
- Complete a Data Transfer Agreement.
- Receive access to datasets.
- Contact Us
If you have any questions about the data or access to it, please contact us.