Metabolomic Profiles of Ultra-Processed vs. Unprocessed/Minimally Processed Foods in Cancer Risk Prediction: Examining Effect Modification by Smoking- and Obesity-Related Metabolites

Principal Investigator

Name
Maryam Farvid

Degrees
Ph.D

Institution
George Mason University

Position Title
Associate Professor

Email
mfarvid@gmu.edu

About this CDAS Project

Study
PLCO (Learn more about this study)

Project ID
PLCO-1882

Initial CDAS Request Approval
Apr 23, 2025

Title
Metabolomic Profiles of Ultra-Processed vs. Unprocessed/Minimally Processed Foods in Cancer Risk Prediction: Examining Effect Modification by Smoking- and Obesity-Related Metabolites

Summary
Ultra-Processed and Unprocessed/Minimally Processed Foods -related metabolomic profiles will be determined and their associations with risk of cancer will be evaluated by considering role of smoking and obesity related metabolites

Aims

Aim 1. Evaluate the associations between metabolomic profiles of ultra-processed vs. unprocessed/minimally processed foods and cancer incidence
Aim 2. Evaluate the effect modification of smoking- and obesity-related metabolites in associations between metabolomic profiles of ultra-processed and unprocessed/minimally processed foods and cancer incidence

Collaborators