Adherence to the EAT-Lancet diet Reduces the Risk of head and neck cancers in American adults: A Prospective Cohort Study
Principal Investigator
Name
Linglong Peng
Degrees
Ph.D.
Institution
The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Position Title
Dr.
Email
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-1398
Initial CDAS Request Approval
Dec 4, 2023
Title
Adherence to the EAT-Lancet diet Reduces the Risk of head and neck cancers in American adults: A Prospective Cohort Study
Summary
Head and neck cancers (HNCs) are malignant tumors typically occur in the oral cavity, pharynx, tongue, vocal cords, larynx, and other areas of the head and neck. The Eat-Lancet diet (ELD) was proposed by The Eat-Lancet Commission in 2019 as a primarily plant-based dietary pattern beneficial for human health and environmental sustainability[1]. Current epidemiological research indicates a strong association between plant-based dietary patterns, such as the Mediterranean Diet (MD), and reduced risk of HNCs[2]. ELD emphasizes a more comprehensive and broader plant-based diet than MD, emphasizing environmental sustainability. While evidence suggests a correlation between ELD and reduced risk of some types of cancers[3,4], there is no specific evidence supporting a direct association between ELD and HNCs. Thus, we aimed to conduct a prospective cohort study to investigate the association between ELD and HNCs.
1. Willett W, Rockström J, Loken B, Springmann M, Lang T, Vermeulen S, et al. Food in the Anthropocene: the EAT-Lancet Commission on healthy diets from sustainable food systems. Lancet. 2019;393:447–92.
2. Li W-Q, Park Y, Wu JW, Goldstein AM, Taylor PR, Hollenbeck AR, et al. Index-based dietary patterns and risk of head and neck cancer in a large prospective study. Am J Clin Nutr. 2014;99:559–66.
3. Xiao Y, Peng L, Xu Z, Tang Y, He H, Gu H, et al. Association between adherence to Eat-Lancet diet and incidence and mortality of lung cancer: A prospective cohort study. Cancer Sci. 2023;
4. Berthy F, Brunin J, Allès B, Fezeu LK, Touvier M, Hercberg S, et al. Association between adherence to the EAT-Lancet diet and risk of cancer and cardiovascular outcomes in the prospective NutriNet-Santé cohort. Am J Clin Nutr. 2022;116:980–91.
1. Willett W, Rockström J, Loken B, Springmann M, Lang T, Vermeulen S, et al. Food in the Anthropocene: the EAT-Lancet Commission on healthy diets from sustainable food systems. Lancet. 2019;393:447–92.
2. Li W-Q, Park Y, Wu JW, Goldstein AM, Taylor PR, Hollenbeck AR, et al. Index-based dietary patterns and risk of head and neck cancer in a large prospective study. Am J Clin Nutr. 2014;99:559–66.
3. Xiao Y, Peng L, Xu Z, Tang Y, He H, Gu H, et al. Association between adherence to Eat-Lancet diet and incidence and mortality of lung cancer: A prospective cohort study. Cancer Sci. 2023;
4. Berthy F, Brunin J, Allès B, Fezeu LK, Touvier M, Hercberg S, et al. Association between adherence to the EAT-Lancet diet and risk of cancer and cardiovascular outcomes in the prospective NutriNet-Santé cohort. Am J Clin Nutr. 2022;116:980–91.
Aims
Our objective is to examine whether following the EAT-Lancet diet are related with a reduced incidence of head and neck cancers in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.
Collaborators
Ling Xiang 1 ,#, Yi Xiao 2, #, Haitao Gu 2, Yunhao Tang 2, Hongmei He 2, Yaxu Wang 2, Xiaorui Ren 2, *, Linglong Peng 2, *
1 Department of Clinical Nutrition, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
2 Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.