Development of AI-Driven Advanced Lung Cancer Screening Models and Risk Factor Analysis
Our research project is driven by the hypothesis that a comprehensive analysis, harnessing clinical information and advanced AI models, including Machine Learning and Deep Learning, can reveal critical risk factors and represent the intricate web of their relationships within the realm of lung cancer for better understanding, allowing to derive personalized predictions of having risk of lung cancer in actionable timeframes. We believe that through acquiring a deep understanding of this complex landscape, we can create a path toward more effective risk-based screening programs and refine the accuracy of patient stratification into high and low-risk categories, as inferred by the models, ultimately resulting in improved outcomes for individuals at risk.
To achieve our research objectives, we proposed a 2 phased approach. In the initial phase, our focus centers on constructing various AI-based models, evaluating and comparing their predictive capabilities for lung cancer incidence across different time horizons, including 1 year, 3 years, and 5 years. In the following research phase, our objective is to assess and explain the relative importance risk factors for the most successful models, carefully studying their role in the development of lung cancer. We also aim to unravel novel or less known risk factors, for a better understanding of those leading to disease in different population groups.
Leveraging state-of-the-art AI methodologies, our aims are two-folded:
- Develop novel AI-based lung cancer risk models that outperform current approaches in lung cancer prediction, and that may enable better personalized risk-based lung cancer screening strategies.
- Identify and gain insights into risk factors leading to the development of lung cancer according to the model predictions
Alba Garin - Senior Researcher (Vicomtech) email@example.com
Xabier Calle - Postdoctoral Researcher (Vicomtech) firstname.lastname@example.org
Isabel Amaya - Predoctoral Researcher (Vicomtech) email@example.com
Eduardo Alonso - Predoctoral Researcher (Vicomtech) firstname.lastname@example.org