Keerthana Clark

B.S.N, M.H.A.

Eastern Virginia Medical School

Student

PLCO (Learn more about this study)

PLCO-1043

Sep 9, 2022

A retrospective study on female-specific characteristics and their association to colorectal cancer using the PLCO Colorectal dataset

There is a gap in evidence to support screening for younger adults and specifically the environmental risk factors for young-onset CRC . Furthermore, there are limited screening guidelines that distinguish females from males (Kim et al., 2015). The current CRC risk scores based on environmental and/or genetic factors developed from past studies had presented a moderate diagnostic efficacy as there is limited research. The purpose of this study is to further investigate a specific sub-group, the female population, and to study specific factors that are in the PLCO dataset that might be potentially associated factors to being diagnosed with CRC. This study is unique as there are very limited studies with a large sample size that looks at the female-specific characteristics in relation to colorectal cancer. This study hopes to further investigate and add to possible risk factors that might have some association with CRC that are specific to the female population. Without a doubt, if there are some possible female-specific risk factors that could be found in this study, there are potential clinical and economic benefits to consider implementing CRC screenings for high-risk females based on these risk factors.