Screening for ovarian cancer in women with a personal or family history of breast or ovarian cancer
Principal Investigator
Name
Nathan Bromham
Degrees
Ph.D.
Institution
National Institute for Health and Care Excellence
Position Title
Senior Systematic Reviewer
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-1002
Initial CDAS Request Approval
Jul 12, 2022
Title
Screening for ovarian cancer in women with a personal or family history of breast or ovarian cancer
Summary
We want to look at the effectiveness of screening for ovarian cancer in the subgroups of women in the PLCO trial with a personal or family history of breast or ovarian cancer. We aim to analyse ovarian cancer incidence, mortality and screening related harms in those subgroups of women.
Aims
We are developing a NICE clinical guideline on familial ovarian cancer: https://www.nice.org.uk/guidance/indevelopment/gid-ng10225
We are looking for evidence comparing ovarian cancer screening with no screening in women with increased familial risk of ovarian cancer to inform this guideline.
This new analysis would be published as an appendix to the guideline and would be freely available.
Collaborators
Laura Berg, National Institute for Health and Care Excellence
Suhayl Kassam, National Institute for Health and Care Excellence
Guideline Development Committee: member list available at https://www.nice.org.uk/guidance/gid-ng10225/documents/committee-member-list