Developing an all-cancer risk model for methodologic research on sampling designs for epidemiologic studies

Principal Investigator

Name
Hormuzd Katki

Institution
NCI

Position Title
Senior Investigator

Email
katkih@mail.nih.gov

About this CDAS Project

Study
PLCO (Learn more about this study)

Project ID
PLCO-961

Initial CDAS Request Approval
Apr 5, 2022

Title
Developing an all-cancer risk model for methodologic research on sampling designs for epidemiologic studies

Summary
We are developing novel efficient epidemiologic sampling designs that collect biospecimens only on an informative subsample. The ideal people to collect biospecimens on are those at highest risk of cancer. We would like to develop an all-cancer risk model purely to examine the value of our new methodology.

Aims

Develop a Cox model for all-cancer risk given key risk factors in common to most cancers (age, sex, race, smoking, BMI, etc)

Collaborators

Barry Graubard (NCI/DCEG)
Mark Ramos (NCI/DCEG)

Related Publications

• Efficient risk-based collection of biospecimens in cohort studies: Designing a prospective study of diagnostic performance for multicancer detection tests.
  Ramos MLF, Chaturvedi AK, Graubard BI, Katki HA
  Am J Epidemiol. 2024 Jul 4 PUBMED