Risk of Prostate Cancer Death in the PLCO Cohort Based on a Four Kallekrein Panel

Principal Investigator

Name
Jonathan Shoag

Degrees
M.D.

Institution
Case Western Reserve University

Position Title
Assistant Professor, Department of Urology, School of Medicine

Email
jxs218@case.edu

About this CDAS Project

Study
PLCO (Learn more about this study)

Project ID
PLCO-912

Initial CDAS Request Approval
Feb 16, 2022

Title
Risk of Prostate Cancer Death in the PLCO Cohort Based on a Four Kallekrein Panel

Summary
Baseline PSA has long been used as a screening and risk assessment tool in men with suspected or confirmed prostate cancer. The goal of this project is to evaluate the association between a four kallikrein panel (total PSA, free PSA, intact PSA, and human kallikrein-related peptidase 2) and prostate cancer mortality for patients in the PLCO Cohort and compare the predictive power of the four kallikrein score with that of baseline PSA.

Aims

- Evaluate the predictive power of a four kallikrein panel for prostate cancer specific mortality

Collaborators

N/A