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Investigation of alternative screening trial endpoints

Principal Investigator
Name
Philip Prorok
Degrees
Ph.D.
Institution
NC I
Position Title
Senior Scientific Program Manager (Contractor)
Email
About this CDAS Project
Study
PLCO (Learn more about this study)
Project ID
PLCO-761
Initial CDAS Request Approval
Apr 5, 2021
Title
Investigation of alternative screening trial endpoints
Summary
I want to explore alternative possible screening trial endpoints. This would involve investigating various functions of staging information and their relationship to cause specific mortality.
Aims

1. Plots of event (endpoint) rates vs time from randomization for several event definitions. Include number of events and number of PY for each arm for each year, and also the rate ratio with upper and lower 95% CIs for each year.

2. For each cancer type the events are stage 4, stage 3+4, cause specific death, stage 4 or cause specific death, stage 3+4 or cause specific death

3. Survival Analysis

Collaborators

none at this time