Korean Lung Cancer Screening Project (K-LUCAS)
Principal Investigator
Name
Yeol Kim
Degrees
M.D., Ph.D
Institution
National Cancer Center, Korea
Position Title
P.I
Email
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-485
Initial CDAS Request Approval
Jun 10, 2019
Title
Korean Lung Cancer Screening Project (K-LUCAS)
Summary
Lung cancer is by far the leading cause of cancer death and has a lower relative survival rate than other types of cancer because most lung cancers are detected at an advanced stage when they are first diagnosed.
Recently, a randomized control trial suggests that low-dose computed tomography (LDCT) enables an early stage detection and it has been increasingly accepted as an efficient screening method for high-risk individuals to reduce lung cancer mortality.
In 2011, The National Lung Screening Trial (NLST) in the U.S. has produced results that screening high-risk smoking groups (who have at least 30 pack-year smoking history and currently smoke or have quit within the past 15 years) aged 55 to 74 years with LDCT reduced lung cancer mortality by 20%.
Based on the evidence, Korean National Cancer Center has developed and published the guideline of lung cancer screening using LDCT for high-risk populations in 2015. The guideline recommends annual LDCT screening for high-risk smoking groups aged 55 to 74 years, with at least 30 pack-year smoking history and current smokers or past smokers who quit smoking within 15 years.
The Korean Lung Cancer Screening project (K-LUCAS), a nationwide, multicenter, prospective study started to evaluate the effectiveness and feasibility of lung cancer screening with LDCT for considering implementation of a national lung cancer screening program in Korea.
Recently, a randomized control trial suggests that low-dose computed tomography (LDCT) enables an early stage detection and it has been increasingly accepted as an efficient screening method for high-risk individuals to reduce lung cancer mortality.
In 2011, The National Lung Screening Trial (NLST) in the U.S. has produced results that screening high-risk smoking groups (who have at least 30 pack-year smoking history and currently smoke or have quit within the past 15 years) aged 55 to 74 years with LDCT reduced lung cancer mortality by 20%.
Based on the evidence, Korean National Cancer Center has developed and published the guideline of lung cancer screening using LDCT for high-risk populations in 2015. The guideline recommends annual LDCT screening for high-risk smoking groups aged 55 to 74 years, with at least 30 pack-year smoking history and current smokers or past smokers who quit smoking within 15 years.
The Korean Lung Cancer Screening project (K-LUCAS), a nationwide, multicenter, prospective study started to evaluate the effectiveness and feasibility of lung cancer screening with LDCT for considering implementation of a national lung cancer screening program in Korea.
Aims
To evaluate the feasibility of implementing a national lung cancer screening program including the use of risk-prediction model for participant selection
Collaborators
Jae Ho Lee, National Cancer Center, Korea
Hyae Young Kim, National Cancer Center, Korea
Jin Mo Goo, Seoul National University College of Medicine, Korea
Juntae Lim, National Caner Center, Korea
Choon-Taek Lee, Seoul National University College of Medicine, Korea
Seung Hun Jang, Hallym University Sacred Heart Hospital
Won-Chul Lee, The Catholic University of Korea
Chan Wha Lee, National Caner Center, Korea
Kui Son Choi, National Caner Center, Korea
Boyoung Park, National Caner Center, Korea
Duk Hyoung Lee, National Caner Center, Korea