Outcomes of stage I non-small cell lung cancer patients treated with surgery versus radiation therapy within the NLST
Principal Investigator
Name
Omar Abdel-Rahman
Degrees
MD
Institution
Avicenna Oncology center
Position Title
Consultant and scientific director
About this CDAS Project
Study
NLST
(Learn more about this study)
Project ID
NLST-445
Initial CDAS Request Approval
Oct 11, 2018
Title
Outcomes of stage I non-small cell lung cancer patients treated with surgery versus radiation therapy within the NLST
Summary
Surgical resection is the currently accepted standard curative treatment for stage I non-small cell lung cancer. However more recently, definitive radiation therapy (particularly through stereotactic body radiation therapy) is being advocated as an acceptable alternative in selected subsets of patients. This remains to be proved through prospective studies.
Aims
1. To determine the differences in all-cause of mortality as well as cancer-specific mortality between patients with stage I disease treated with surgery versus radiation therapy.
2. To determine the risk of second primary malignancy development following initial radical treatment of stage I lung cancer.
Collaborators
1. Dr. Omar Abdel-Rahman
Related Publications
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Impact of current versus former smoking status on the outcomes of non-metastatic non-small cell lung cancer treated with upfront surgery; findings from the National Lung Screening Trial.
Abdel-Rahman O
Expert Rev Respir Med. 2019 Jun; Volume 13 (Issue 6): Pages 585-591 PUBMED