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About this Publication
Title
Design and evolution of the data management systems in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial.
Pubmed ID
11189686 (View this publication on the PubMed website)
Publication
Control Clin Trials. 2000 Dec; Volume 21 (Issue 6 Suppl): Pages 329S-348S
Authors

Hasson MA, Fagerstrom RM, Kahane DC, Walsh JH, Myers MH, Caughman C, Wenzel B, Haralson JC, Flickinger LM, Turner LM, Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial Project Team

Abstract

This paper describes the design and evolution of the data management systems developed in support of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. These systems span platforms from stand-alone computers to distributed systems on local area networks to mainframes. Allowing all of these systems to share appropriate information electronically introduces integration, synchronization, testing, and support challenges. For each platform, applications were developed to handle data entry, editing, trial management, reporting, telecommunications, and data sharing. Approaches to issues such as level of data access, integration with other, existing applications, and handling the expansion of the protocol are discussed.

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