Identifying Optimal Cohort for Renal Cell Cancer Screening
There are countries where ultrasound is used by primary care physicians to help with their physical exam. There remains a question whether there are populations of sufficient risk to justify screening of certain populations for kidney cancer. Age, BMI and smoking intensity are both risk factors for renal cell carcinoma.
The questions we seek to address include determining the true incidence of kidney cancer in a high risk cohort of subjects with a history of heavy smoking,
We will try to identify the risk of kidney cancer in the NLST stratified by age, gender, BMI and smoking history to try to identify those subjects with highest risk of kidney cancer. This will help identify the highest risk patients for a possible kidney cancer screening trial.
Identify the risk of kidney cancer in the NLST based on age, gender, ethnicity, BMI and smoking history.
We want to identify which subject group had the highest risk of kidney cancer and what incidence was during the study.
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Renal-cell carcinoma risk estimates based on participants in the prostate, lung, colorectal, and ovarian cancer screening trial and national lung screening trial.
Lotan Y, Karam JA, Shariat SF, Gupta A, Roupret M, Bensalah K, Margulis V
Urol. Oncol. 2015 Nov; Volume [Epub ahead of print]: Pages [Epub ahead of print] PUBMED