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Applying LungRads to NLST

Principal Investigator
Name
Paul Pinsky
Institution
NCI
Position Title
Acting Chief, Early Detection Branch
Email
About this CDAS Project
Study
NLST (Learn more about this study)
Project ID
NLST-79
Initial CDAS Request Approval
Jun 24, 2014
Title
Applying LungRads to NLST
Summary
LungRADs is a scoring system for low-dose CT screening developed by the American College of Radiology (ACR) that is analogous to BIRADS for mammography. We are interested in the LungRads classifications when it is applied in NLST.
Aims

1. To determine the distribution of LungRads scores for subjects with and without cancer in NLST.
2. To assess sensitivity, specificity and PPV using LungRads applied to NLST, using the LungRads cutoff of 3 to define a positive screen.
3. To ascertain the reasons for false negative screens using LungRads.

Collaborators

Ella Kazerooni, Univ of Michigan

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