Patient Factors Associated with A Positive Finding on First CT Screening Exam

Principal Investigator

Name
Alex Balekian

Institution
University of Southern California

Position Title
Assistant Professor

Email
alex.balekian@med.usc.edu

About this CDAS Project

Study
NLST (Learn more about this study)

Project ID
NLST-76

Initial CDAS Request Approval
Jun 6, 2014

Title
Patient Factors Associated with A Positive Finding on First CT Screening Exam

Summary
In clinical practice, practitioners often encounter patients who ask whether CT screening is appropriate for them. Based on the most recent ACCP guidelines, patients at high-risk should have CT screening offered, and not necessarily performed. Although we know that 40% of patients will have positive scans, with ultimately 96% of them being false positives, arming practitioners with the knowledge of a patient's baseline risk of having a positive scan might be helpful in counseling patients whether to undergo CT screening in the first place.

Aims

1) To determine patient-specific factors that predict a positive screen on first CT screening exam

2) To determine patient-specific factors that predict a positive scan within two years given a normal first screening exam

Collaborators

Michael Gould, Kaiser Permanente Southern California
Gerard Sylvestri, Medical University of South Carolina

Related Publications

• Factors Associated with a Positive Baseline Screening Exam Result in the National Lung Screening Trial.
  Balekian AA, Tanner NT, Fisher JM, Silvestri GA, Gould MK
  Ann Am Thorac Soc. 2016 Jul PUBMED