Long term lung cancer risk of non-calcified nodules
This studies aims to assess the long term lung cancer risk of such nodules. If they are associated with long term increased risk, after allowing for any current actual cancers to be diagnosed, this provides some evidence that they are a valid surrogate.
Specific aims:
1: W will analyze the risk of lung cancer associated with lung nodules, after allowing sufficient time (around 3 years) for any actual current cancer to be diagnosed. We will analyze outcomes by lung (left/right) and lung lobe; thus we will see if a nodule in a given lung (lobe) is associated with cancer (starting 3 years after the screen that noted the nodule) in that same lung (lobe).
2. To analyze the above risk by nodule size, stability and type.
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Long-term cancer risk associated with lung nodules observed on low-dose screening CT scans.
Pinsky P, Gierada DS
Lung Cancer. 2020 Jan; Volume 139: Pages 179-184 PUBMED -
Short- and long-term lung cancer risk associated with noncalcified nodules observed on low-dose CT.
Pinsky PF, Nath PH, Gierada DS, Sonavane S, Szabo E
Cancer Prev Res (Phila). 2014 Apr; Volume [Epub ahead of print]: Pages [Epub ahead of print] PUBMED