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BMI, weight change, and site-specific cancer incidence in PLCO

Principal Investigator

Name
Cari Kitahara

Degrees
PhD

Institution
NCI, DCEG, NEB

Position Title
Research fellow

Email
kitaharac@mail.nih.gov

About this CDAS Project

Study
PLCO (Learn more about this study)

Project ID
PLCO-45

Initial CDAS Request Approval
Aug 2, 2013

Title
BMI, weight change, and site-specific cancer incidence in PLCO

Summary
We propose a pooled analysis of PLCO and the NIH-AARP Diet and Health Study to examine BMI at various ages throughout adulthood, BMI change, and total and site-specific cancer incidence.

Aims

1. Examine the associations of BMI in young adulthood (approximately ages 17-21), in middle-to-older adulthood (approximately age 50), and at baseline with the risks of total and site-specific cancers.
2. Examine associations for BMI change between young adulthood and middle-to-older adulthood on the risks of total and site-specific cancers.

Site-specific cancers include:

By site: female breast, endometrial, ovarian, liver, kidney, thyroid, pancreatic, non-Hodgkin lymphoma, multiple myeloma, leukemia, colorectal, lung, and prostate
By site and histology: esophageal adenocarcinoma, gastric cardia

Collaborators

Wen-Yi Huang, NCI
Patricia Hartge, NCI
Amy Berrington de Gonzalez, NCI
Steven Moore, NCI
Philip Rosenberg, NCI

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