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Mortality reductions produced by a sustained low-dose helical CT screening program for lung cancer

Principal Investigator
Name
James Hanley
Degrees
PhD
Institution
McGill University
Position Title
Professor
Email
About this CDAS Project
Study
NLST (Learn more about this study)
Project ID
NLST-19
Initial CDAS Request Approval
May 24, 2013
Title
Mortality reductions produced by a sustained low-dose helical CT screening program for lung cancer
Summary
The NLST is a rigorous, statistically large,  high-compliance trial of close-to-contemporary screening technology. It established that 3 rounds of CT screening led to a statistically nonzero reduction in lung cancer mortality over the follow-up period reported.

Using the information from this trial, we would like to estimate the long-term benefits that would be produced by a sustained screening program. To do this, we will use time-specific data, along with appropriate modelling, to project the long-term mortality reductions, and operating characteristics, expected in a sustained screening program.
Aims

Estimate
(i)the long-term benefits that would be produced by a sustained screening program
(ii) operating characteristics
expected in a sustained screening program.

Collaborators

Zhihui(Amy) Liu, Dept of Epidemiology, Biostatistics and Occupational Health, McGill University

Erin Strumpf, Departments of Economics and of Epidemiology, Biostatistics and Occupational Health, McGill University

Nandini Dendukuri, Department of Epidemiology, Biostatistics and Occupational Health, McGill University

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