TTFC and COPD in PLCO
Principal Investigator
Name
Neil Caporaso
Institution
NCI, DCEG, GEB
Position Title
Branch Chief
Email
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-36
Initial CDAS Request Approval
May 22, 2013
Title
TTFC and COPD in PLCO
Summary
We have recently shown that TTFC (Time to First Cigarette), the 2nd question in the Fagerstrom Index, is related to lung cancer risk in PLCO. We now want to examine the same question regarding chronic bronchitis and emphysema in PLCO.
Aims
1. Is TTFC related to chronic bronchitis and emphysema, after adjustment for the usual COPD risk factors, i.e. age, gender, race, smoking status.
2. Is TTFC related to abnormalities on chest xray after similar adjustment?
Collaborators
Fangyi Gu
Sholom Wacholfer
Kristin Guertin
Related Publications
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Time to First Morning Cigarette and Risk of Chronic Obstructive Pulmonary Disease: Smokers in the PLCO Cancer Screening Trial.
Guertin KA, Gu F, Wacholder S, Freedman ND, Panagiotou OA, Reyes-Guzman C, Caporaso NE
PLoS ONE. 2015; Volume 10 (Issue 5): Pages e0125973 PUBMED