Dietary Glycemic Index, Glycemic Load, and Risk of Lung Cancer
Principal Investigator
Name
Kanran Wang
Degrees
M.D., Ph.D.
Institution
Chongqing University Cancer Hospital
Position Title
research fellow, attending doctor
Email
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-1829
Initial CDAS Request Approval
Feb 19, 2025
Title
Dietary Glycemic Index, Glycemic Load, and Risk of Lung Cancer
Summary
Lung cancer remains the most commonly diagnosed cancer in males and the fourth most prevalent in females worldwide. While cigarette smoking remains the most established risk factor for lung cancer, responsible for ~85% of cases in developed nations, a growing body of evidence indicates that modifiable dietary patterns may also significantly influence lung cancer risk. The glycemic index (GI) classifies carbohydrate-containing foods based on their postprandial blood glucose impact. Glycemic load (GL), calculated by multiplying GI by a food's digestible carbohydrate content per serving, reflects the quantity and glycemic potency of carbohydrates consumed. There is considerable inconsistency in results regarding the association of dietary glycemic index (GI) and glycemic load (GL) with lung cancer risk. Therefore we aim to investigate this relationship in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) cohort.
Aims
1. Investigate the associations of GI and GL with lung cancer risk among aging American adults in the PLCO cohort.
Collaborators
Jinping Wang MD Chongqing University Central Hospital
Wei Zhou MD, PhD Chongqing University Cancer Hospital
YYongzhong Wu MD, PhD Chongqing University Cancer Hospital