Subgroup Analysis of Primary NLST Mortality Endpoint

Principal Investigator

Name
Grant Izmirlian

Degrees
Ph.D.

Institution
NCI

Position Title
Mathematical Statistician

Email
izmirlig@mail.nih.gov

About this CDAS Project

Study
NLST (Learn more about this study)

Project ID
NLST-10

Initial CDAS Request Approval
Feb 1, 2013

Title
Subgroup Analysis of Primary NLST Mortality Endpoint

Summary
We wish to analyze the effect of screening on lung cancer mortality by age group, sex, and smoking status using weighted cox proportional hazards regression. We would also like to examine cancer survival by histology subtype.

Aims

We wish to analyze the effect of screening on lung cancer mortality by age group, sex, and smoking status using weighted cox proportional hazards regression. We would also like to examine cancer survival by histology subtype.

Collaborators

Richard Fagerstrom
Phil Prorok

Related Publications

• The National Lung Screening Trial: results stratified by demographics, smoking history, and lung cancer histology.
  Pinsky PF, Church TR, Izmirlian G, Kramer BS
  Cancer. 2013 Nov; Volume 119 (Issue 22): Pages 3976-83 PUBMED