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Quantification of Interstitial Lung Abnormalities Using Data from the National Lung Screening Trial

Principal Investigator
Name
Hyungjin Kim
Degrees
M.D., Ph.D.
Institution
Seoul National University Hospital
Position Title
Clinical associate professor
Email
About this CDAS Project
Study
NLST (Learn more about this study)
Project ID
NLST-1350
Initial CDAS Request Approval
Nov 5, 2024
Title
Quantification of Interstitial Lung Abnormalities Using Data from the National Lung Screening Trial
Summary
Interstitial lung abnormalities (ILA) have been associated with an increased risk of lung cancer and higher mortality rates. However, studies focusing on quantifying ILA using large-scale screening data are limited.
Aims

This study aims to determine the prevalence of ILA in all available CT scans from the National Lung Screening Trial. Additionally, quantitative thresholds for defining ILA will be assessed. Associations between ILA and various outcomes, including lung cancer incidence and mortality, will also be examined. Changes in ILA over time will be evaluated using T0, T1 and T2 scans.

Collaborators

Taehee Lee, Seoul National University Hospital
Jonghyuk Lee, Seoul National University Hospital