Skip to Main Content

An official website of the United States government

Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit  cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at OPM.gov.

Principal Investigator
Name
Choonsik Lee
Degrees
PhD
Institution
National Cancer Institute
Position Title
Senior Investigator
Email
About this CDAS Project
Study
NLST (Learn more about this study)
Project ID
NLST-1307
Initial CDAS Request Approval
Aug 19, 2024
Title
Cancer risk after radiation exposure from low dose lung cancer screening (NCI Only version of NLST-1127)
Summary
Lung cancer screening using a low dose chest CT scans has proven to be effective in early detection of lung cancer and reduced mortality. However, a lingering concern is the radiation-related cancer risk associated with these low dose chest CT scans. The broader implications regarding cancer incidence due to radiation exposure remain inadequately explored.
Aims

This study aims to assess the non-lung cancer risk in lung cancer screening participants following exposure to low dose chest CT scans. The primary outcome is the incidence rates of cancers, excluding lung cancer, in individuals who have been exposed to a CT scan more than one year prior to any cancer diagnosis. This will be compared to the non-lung cancer incidence rates in a control group comprising individuals who underwent a chest X-ray screening.

Collaborators

Soon Ho Yoon, Radiology, Seoul National University Hospital, Seoul, Republic of Korea
Hyunsook Hong, Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Republic of Korea