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Principal Investigator
Martin Tammemagi
Henry Ford Health System
Position Title
Associate Professor of Epidemiology
About this CDAS Project
NLST (Learn more about this study)
Project ID
Initial CDAS Request Approval
Aug 22, 2008
Smoking Cessation and Relapse in the National Lung Screening Trial
Participation in a lung cancer screening trial may heighten motivation to quit smoking, especially given that study participants were enrolled on the basis that they were at high risk for developing lung cancer and were concerned enough to enroll in the study. Understanding smoking behavior during lung cancer screening and the teachable moment may help develop methods to more effectively administer smoking cessation programs, as currently available programs are lamentably unsuccessful. Tobacco smoking is a highly addictive behavior and many individuals who quit smoking relapse after periods of abstinence. Data on the rates of smoking cessation and relapse following enrollment in a lung screening trial are incomplete. The proposed study plans to analyze longitudinal prospective smoking data in the NLST to estimate rates of smoking cessation and relapse. In addition, the associations between sociodemographic, medical history, smoking history and screening factors and smoking cessation and relapse will be evaluated.

This study of National Lung Screening Trial (NLST) participants plans to develop a better understanding of smoking behavior by evaluating the following: (1) in individuals who were current smokers at the time of study enrollment, the rates of cessation (quitting or substantially reducing smoking intensity) and factors associated with cessation, including sociodemographic, socioeconomic, medical, clinical and screening factors; (2) in individuals who were former smokers at the time of NLST enrollment, the rates of smoking relapse and factors associated with relapse.

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