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Principal Investigator
Name
Antonio Jesus Diaz Honrubia
Degrees
Ph.D.
Institution
Universidad Politécnica de Madrid
Position Title
Associate Professor (tenured)
Email
About this CDAS Project
Study
NLST (Learn more about this study)
Project ID
NLST-1273
Initial CDAS Request Approval
Jun 17, 2024
Title
AI-Enhanced Exploration of Lung Cancer Risk Factors
Summary
Lung cancer poses a significant global public health challenge, with millions of new cases diagnosed annually and alarmingly low survival rates. Despite existing screening efforts, timely and accurate diagnosis remains elusive. The research project is founded on the belief that through comprehensive representation and analysis of multimodal data using advanced AI algorithms, including Machine Learning and Deep Learning, we can enhance our understanding of lung cancer etiology. This advancement holds the potential to improve screening programs and develop more effective risk prediction models, refining patient stratification, identifying risk factors, and predicting lung cancer risk more accurately based on clinical data.
To achieve the research objectives, we will develop advanced lung cancer screening methods by integrating structured clinical data and utilizing advanced analytics. We’ll also refine existing case detection algorithms and improve risk estimation models through systematic analysis of structured data sets and advanced AI techniques. Additionally, we’ll conduct detailed investigations to gain deeper insights into tumor progression, focusing on structured data related to tumor characteristics and patient outcomes. Through these efforts, we aim to detect and understand key risk factors associated with lung cancer, leading to improved clinical outcomes.
Aims

- Develop knowledge representation and advanced AI models for lung cancer risk prediction, improving screening and interventions for better patient outcomes.

- Understand underlying risk factors associated with lung cancer development, utilizing predictive model insights and analytical findings.

- Gain comprehensive insights into lung cancer tumor microenvironment diversity, identifying patterns linked to disease progression.

Collaborators

Alejandro Rodríguez González – Associate Professor (CTB-UPM) alejandro.rg@upm.es
Guillermo Antonio Vigueras González – Associate Professor (CTB-UPM) guillermo.vigueras@upm.es
Paloma Tejera Nevado – Postdoctoral Researcher (CTB-UPM) paloma.tejera@upm.es
Lucía Prieto Santamaría – Postdoctoral Researcher (CTB-UPM) lucia.prieto.santamaria@upm.es
Delia Aminta Moreno Perdomo – Predoctoral Researcher (CTB-UPM) da.moreno@upm.es