Study of Effectiveness of Computer Aided Detection of Missed Cancers

Principal Investigator

Name
Matthew Freedman

Institution
Georgetown University

Email
freedmmt@georgetown.edu

About this CDAS Project

Study
PLCO (Learn more about this study)

Project ID
2006-0095

Initial CDAS Request Approval
Jul 1, 2006

Title
Study of Effectiveness of Computer Aided Detection of Missed Cancers

Summary
On chest radiographs, skilled radiologists have been shown in several studies to miss up to 1/3 or more of cancers that can be detected in retrospect. Computer aids to detection have been shown to enhance this detection rate, resulting in up to 21% more cancers detected. The goal is to determine whether radiologists using the most modern CAD systems would have been able to detect the cancers detected in the PLCO on the radiograph obtained one year prior to their actual detection if they had used computer aids.

Aims

The specific aim is to test a modern computer program for the detection of lung cancer on the one year prior chest radiographs of subjects who were identified to have a lung cancer on their next screening chest radiograph.