A Research Investigation on the Association between Various Dietary Patterns and the Incidence Risk of Renal Cancer.
Principal Investigator
Name
MENGTONG WANG
Degrees
M.D
Institution
Beijing Chao-Yang Hospital,Capital Medical University
Position Title
Attending
Email
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-1366
Initial CDAS Request Approval
Oct 31, 2023
Title
A Research Investigation on the Association between Various Dietary Patterns and the Incidence Risk of Renal Cancer.
Summary
Renal cancer is the second most lethal malignancy in the urinary system. According to the latest GLOBOCAN data, there were approximately 430,000 new cases of kidney cancer and 180,000 deaths in 2020 [1]. Multiple behavioral and environmental factors are associated with the development and progression of kidney cancer, including use of painkillers, smoking, obesity, hypertension, and chronic kidney disease [2]. Numerous studies have investigated the relationship between diet and kidney cancer risk, but analysis of risk associated with individual nutrients or foods (such as alcohol consumption, vitamin D, coffee, fruits and vegetables) has yielded inconsistent results in epidemiological studies [3-7].Hence, our objective is to examine the association between dietary pattern and renal cancer using data from the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial prospective cohort.
References:
[1]. Sung, H., et al., Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: a cancer journal for clinicians, 2021. 71(3): p. 209-249.
[2]. Capitanio, U., et al., Epidemiology of Renal Cell Carcinoma. European urology, 2019. 75(1): p. 74-84.
[3]. Schouten, L.J., et al., Alcohol consumption and mutations or promoter hypermethylation of the von Hippel-Lindau gene in renal cell carcinoma. Cancer Epidemiol Biomarkers Prev, 2008. 17(12): p. 3543-50.
[4]. Karami, S., et al., Vitamin d pathway genes, diet, and risk of renal cell carcinoma. Int J Endocrinol, 2010. 2010: p. 879362.
[5]. Rhee, J., R.K. Lim and M.P. Purdue, Coffee consumption and risk of renal cancer: a meta-analysis of cohort evidence. Cancer Causes Control, 2022. 33(1): p. 101-108.
[6]. Daniel, C.R., et al., Intake of fiber and fiber-rich plant foods is associated with a lower risk of renal cell carcinoma in a large US cohort. Am J Clin Nutr, 2013. 97(5): p. 1036-43.
[7]. Michels, K.B. and M.B. Schulze, Can dietary patterns help us detect diet-disease associations? Nutr Res Rev, 2005. 18(2): p. 241-8.
References:
[1]. Sung, H., et al., Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: a cancer journal for clinicians, 2021. 71(3): p. 209-249.
[2]. Capitanio, U., et al., Epidemiology of Renal Cell Carcinoma. European urology, 2019. 75(1): p. 74-84.
[3]. Schouten, L.J., et al., Alcohol consumption and mutations or promoter hypermethylation of the von Hippel-Lindau gene in renal cell carcinoma. Cancer Epidemiol Biomarkers Prev, 2008. 17(12): p. 3543-50.
[4]. Karami, S., et al., Vitamin d pathway genes, diet, and risk of renal cell carcinoma. Int J Endocrinol, 2010. 2010: p. 879362.
[5]. Rhee, J., R.K. Lim and M.P. Purdue, Coffee consumption and risk of renal cancer: a meta-analysis of cohort evidence. Cancer Causes Control, 2022. 33(1): p. 101-108.
[6]. Daniel, C.R., et al., Intake of fiber and fiber-rich plant foods is associated with a lower risk of renal cell carcinoma in a large US cohort. Am J Clin Nutr, 2013. 97(5): p. 1036-43.
[7]. Michels, K.B. and M.B. Schulze, Can dietary patterns help us detect diet-disease associations? Nutr Res Rev, 2005. 18(2): p. 241-8.
Aims
(1) Evaluate the association between different dietary pattern(DASH\Mediterranean diet\DRRD,etc) and risk of renal cancer.
(2) Investigate the interactions of dietary pattern with BMI, smoking, physical activity, drug use, vitamin supplement and type 2 diabetes on renal cancer risk.
Collaborators
(1)Yuanhao Chen, Department of Urology, Beijing Chaoyang Hospital Affiliated To Capital Medical University, Beijing, China
(2)Song Zeng, Department of Urology, Beijing Chaoyang Hospital Affiliated To Capital Medical University, Beijing, China
(3)Xiaopeng Hu, Department of Urology, Beijing Chaoyang Hospital Affiliated To Capital Medical University, Beijing, China