Ultra-processed food consumption and risk of prostate cancer: results from a large prospective multicenter study
Principal Investigator
Name
yadong Li
Degrees
M.M
Institution
The Second Affiliated Hospital of chongqing medical university
Position Title
Dr
Email
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-1201
Initial CDAS Request Approval
Apr 19, 2023
Title
Ultra-processed food consumption and risk of prostate cancer: results from a large prospective multicenter study
Summary
Prostate cancer is the second most common malignancy and the fifth cause of cancer-related death in men, with an estimated >1,400,000 new patients and >375,000 deaths worldwide each year, with a growing incidence (1). The established risk factors for prostate cancer include age, ethnicity, and germline mutation, which cannot be modified. Therefore, it is becoming vital importance to identify modifiable risk factors (2). Intriguingly, dietary factors may play an indispensable role in the development and procession of prostate cancer.
Ultra-processed foods with having a higher content of total fat, and added sugar and salt, along with a lower fibre and vitamin density was associated with the risk of dyslipidaemia overweight, obesity, and hypertension. Although some studies have been explored the association between ultra-processed food consumption and prostate cancer risk (3, 4), no prospective multicenter cohort accurately evaluated this potential association. Hence, we sought to investigate this potential association in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial.
Ultra-processed foods with having a higher content of total fat, and added sugar and salt, along with a lower fibre and vitamin density was associated with the risk of dyslipidaemia overweight, obesity, and hypertension. Although some studies have been explored the association between ultra-processed food consumption and prostate cancer risk (3, 4), no prospective multicenter cohort accurately evaluated this potential association. Hence, we sought to investigate this potential association in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial.
Aims
To investigate the prospective associations between ultra-processed food consumption and risk of prostate cancer in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial
Collaborators
(1) Chuan Liu, Department of urology , the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
(2) Liang Gao, Department of urology , the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.