Ultra-processed food consumption and cancer-related mortality in patients with colorectal, lung, prostate, or breast cancer: a post hoc analysis of the PLCO cancer screening trial
Principal Investigator
Name
Guo-Chao Zhong
Degrees
Ph.D.
Institution
The Second Affiliated Hospital of Chongqing Medical University
Position Title
Director of the department
Email
About this CDAS Project
Study
PLCO
(Learn more about this study)
Project ID
PLCO-1180
Initial CDAS Request Approval
Mar 20, 2023
Title
Ultra-processed food consumption and cancer-related mortality in patients with colorectal, lung, prostate, or breast cancer: a post hoc analysis of the PLCO cancer screening trial
Summary
The number of cancer patients is rabidly increasing worldwide. In the USA, there are around 16.9 million peoples who are currently living with cancer (1). Given the huge burden of cancer patients globally, it is necessary and urgent to identify modifiable risk factors for improving the prognosis of this population.
Dietary habits have been indicated to play an important role in determining the prognosis of cancer survivors. For example, a recent meta-analysis found that high vegetable consumption was inversely associated with overall mortality in survivors of head and neck (2). Ultra-processed food consumption has been associated with an increased risk of death. However, to our knowledge, no prospective cohort study has accurately evaluated the potential association between ultra-processed food consumption and mortality in cancer patients. Hence, we sought to examine this potential association in breast, colorectal, lung, and prostate cancer patients.
Refs.
(1) Cao C, Friedenreich CM, Yang L. Association of Daily Sitting Time and Leisure-Time Physical Activity With Survival Among US Cancer Survivors. JAMA Oncol. 2022;8(3):395-403.
(2) Hurtado-Barroso S, Trius-Soler M, Lamuela-Raventós RM, Zamora-Ros R. Vegetable and Fruit Consumption and Prognosis Among Cancer Survivors: A Systematic Review and Meta-Analysis of Cohort Studies. Adv Nutr. 2020;11(6):1569-1582.
Dietary habits have been indicated to play an important role in determining the prognosis of cancer survivors. For example, a recent meta-analysis found that high vegetable consumption was inversely associated with overall mortality in survivors of head and neck (2). Ultra-processed food consumption has been associated with an increased risk of death. However, to our knowledge, no prospective cohort study has accurately evaluated the potential association between ultra-processed food consumption and mortality in cancer patients. Hence, we sought to examine this potential association in breast, colorectal, lung, and prostate cancer patients.
Refs.
(1) Cao C, Friedenreich CM, Yang L. Association of Daily Sitting Time and Leisure-Time Physical Activity With Survival Among US Cancer Survivors. JAMA Oncol. 2022;8(3):395-403.
(2) Hurtado-Barroso S, Trius-Soler M, Lamuela-Raventós RM, Zamora-Ros R. Vegetable and Fruit Consumption and Prognosis Among Cancer Survivors: A Systematic Review and Meta-Analysis of Cohort Studies. Adv Nutr. 2020;11(6):1569-1582.
Aims
To examine the potential associations between ultra-processed food consumption and cancer-related mortality in breast, colorectal, lung, and prostate cancer patients.
Collaborators
(1) Qian Zhu, Department of Nutrition and Food Hygiene, School of Public Health and Management, Chongqing Medical University, Chongqing, China
(2) Chun-Rui Wang, Department of Infectious Diseases, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China