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Principal Investigator
Name
Douglas Chang
Degrees
M.D.
Institution
National Institute of Diabetes and Digestive and Kidney Diseases
Position Title
Physician/Investigator
Email
About this CDAS Project
Study
IDATA (Learn more about this study)
Project ID
IDATA-54
Initial CDAS Request Approval
Mar 25, 2022
Title
Comparison of self-reported water intake against recovery biomarkers
Summary
Prior evidence suggests that low water consumption and underhydration is linked with negative health consequences such as diabetes, urinary tract infections, and cardiovascular strain and that increased consumption is associated with beneficial health effects including decreased risk of kidney stones, improved cognitive performance, and glucose regulation. Hydration has also been shown to influence macronutrient substrate oxidation which has been linked with weight gain. Epidemiological studies of nutrition have made important contributions to understanding the relationship between dietary factors and disease. Such studies rely upon tools based on self-reported dietary intake which are subject to measurement error and require validation. Advances in understanding the link between water intake and health have been hampered by the limited ability to assess water intake at the population level. Though attempts have been made to develop and validate fluid-specific assessment tools including against water intake-related biomarkers such as doubly labeled water (DLW), more accurate tools are still elusive. Water intake in free-living conditions can be measured from water turnover derived from DLW that also accounts for metabolic water. The Automated Self-Administered 24-hour Dietary Assessment Tool (ASA24) is a freely available, web-based, automatically coded, self-administered recall instrument. How well water intake from ASA24 and other self-reported dietary assessment tools (e.g., Diet History Questionnaire (DHQ) II; 4-d food records) compares with known biomarkers such as DLW is unclear.
Aims

To compare water intake from self-reported dietary assessment tools (e.g., ASA24, DHQ II, and 4-d food records) against biomarkers (e.g., DLW-derived measure of water intake).

Collaborators

Stavros A. Kavouras (Arizona State University)
Dale A. Schoeller (University of Wisconsin-Madison)
Susanne B. Votruba (National Institute of Diabetes and Digestive and Kidney Diseases)
Emma J. Stinson (National Institute of Diabetes and Digestive and Kidney Diseases)
Jonathan Krakoff (National Institute of Diabetes and Digestive and Kidney Diseases)
Kirsten A. Herrick (National Cancer Institute)
Heather R. Bowles (National Cancer Institute)
Jill Reedy (National Cancer Institute)

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