Douglas Chang

M.D.

National Institute of Diabetes and Digestive and Kidney Diseases

Physician/Investigator

IDATA (Learn more about this study)

IDATA-54

Mar 25, 2022

Comparison of self-reported water intake against recovery biomarkers

Prior evidence suggests that low water consumption and underhydration is linked with negative health consequences such as diabetes, urinary tract infections, and cardiovascular strain and that increased consumption is associated with beneficial health effects including decreased risk of kidney stones, improved cognitive performance, and glucose regulation. Hydration has also been shown to influence macronutrient substrate oxidation which has been linked with weight gain. Epidemiological studies of nutrition have made important contributions to understanding the relationship between dietary factors and disease. Such studies rely upon tools based on self-reported dietary intake which are subject to measurement error and require validation. Advances in understanding the link between water intake and health have been hampered by the limited ability to assess water intake at the population level. Though attempts have been made to develop and validate fluid-specific assessment tools including against water intake-related biomarkers such as doubly labeled water (DLW), more accurate tools are still elusive. Water intake in free-living conditions can be measured from water turnover derived from DLW that also accounts for metabolic water. The Automated Self-Administered 24-hour Dietary Assessment Tool (ASA24) is a freely available, web-based, automatically coded, self-administered recall instrument. How well water intake from ASA24 and other self-reported dietary assessment tools (e.g., Diet History Questionnaire (DHQ) II; 4-d food records) compares with known biomarkers such as DLW is unclear.