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Investigation of alternative screening trial endpoints

Principal Investigator
Name
Phil Prorok
Degrees
Ph.D.
Institution
NCI
Position Title
Senior Scientific Program Manager (Contractor)
Email
About this CDAS Project
Study
MINN (Learn more about this study)
Project ID
MINN-1
Initial CDAS Request Approval
Apr 15, 2021
Title
Investigation of alternative screening trial endpoints
Summary
I want to explore alternative possible screening trial endpoints. This would involve investigating various functions of staging information and their relationship to cause specific mortality.
Aims

1. Plots of event (endpoint) rates vs time from randomization for several event definitions. Include number of events and number of PY for each arm for each year, and also the rate ratio with upper and lower 95% CIs for each year.

2. For annual and biennial fecal occult blood test: dukes D, dukes C+D, colorectal death, dukes D or death, dukes C+D or death

3. Survival Analysis

Collaborators

none at this time