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A systematic evaluation of dietary, hormone， and behavioral factors associated with glioma risk

Principal Investigator
Name
Chuan Shao
Degrees
M.D
Institution
Chongqing General Hospital, Chongqing University
Position Title
researcher, attending physician
Email
About this CDAS Project
Study
PLCO (Learn more about this study)
Project ID
PLCO-712
Initial CDAS Request Approval
Jan 14, 2021
Title
A systematic evaluation of dietary, hormone， and behavioral factors associated with glioma risk
Summary
Gliomas are the most frequently type of primary brain tumors with high invasiveness and poor prognosis. With the exception of high Ionizing radiation and some rare hereditary syndromes, few well-established risk factors for glioma were identified. Generally, gliomas are more often with increasing age, male gender, and white race. The finding of the difference between ethnicities and genders indicated that both genetic and environmental factors may play essential roles in development of glioma. Therefore, we plan to perform a systematic evaluation of dietary, hormone and behavioral factors associated with glioma risk.

Our study is to assess the association between glioma risk and lifestyle and some personal exposure factors. If the data are available, we plan to include data about body mass index, physical activity, coffee, cigarette smoking, alcohol intake, and vegetables and fruits consumption. Moreover, data about exogenous hormone use, reproductive and menstrual factors and glioma risk in women are also needed.
Aims

We plan to systematically evaluate the associations between environmental and dietary, hormone and behavioral factors (including dietary habits, nutrient supplements, NSAID use, body mass index, physical activity, personal medical history, exogenous and endogenous hormones in women, and sleep conditions) and glioma risk.

Collaborators

Xiaoya Wang; The Affiliated Hospital of North Sichuan Medical College, Nanchong
Hui Tang; The Second Clinical Medical College, North Sichuan Medical College
Jiaquan He;The Second Clinical Medical College, North Sichuan Medical College
Nan Wu; Chongqing General Hospital, University of Chinese Academy of Sciences
Pan Wang; Chongqing General Hospital, University of Chinese Academy of Sciences

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